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Biophysics of Membranes : 20.3.2015

Bachelor Course. Block 3, 2014 / 2015, Skema B

schedule: Tuesday 13-17, Friday 8-10 / Excercises: Friday 10-12
place: Aud. C, Blegdamsvej 17
first class: Tuesday, Febr. 3, 13:00, Aud. C
exam: Friday, April 10, 2014

Link to KU kurser page Link to Time and Place --> current handout and other material

ABSTRACT:
Membranes are those components of a biological cell that separate the functional units and form the spacial boundaries of the organelles. The major building block is the lipid bilayer into which proteins are embedded. Membranes maintain the chemical potentials of the cell components, and regulate transport. The membrane proteins have many catalytic and transport properties. The membranes themselves display all kinds of interesting physical properties: They can melt and they are characterized by elastic constants, which are important for membrane fusion and structural changes and depend on the melting. Furthermore, membranes may be permeable to certain molecules and they form lateral domains of their components, which are highly discussed in the context of cell signaling. This course will introduce into the thermodynamics of membranes, accompanied by electrostatics of layers, hydrophobic effect, elastic theory and lipid-protein interactions.

contact: T. Heimburg, NBI, Blegdamsvej 17, Kc9 - Tel: 3532 5389. E-mail: theimbu@nbi.dk